Certain nasal sprays recalled as a result of risks together with seizure and demise


About Certain
Certainty (also known as epistemic certainty or objective certainty) is an epistemic property of beliefs which a person has no rational grounds for doubting. One standard way of defining epistemic certainty is that a belief is certain if and only if the person holding that belief could not be mistaken in holding that belief. Other common definitions of certainty involve the indubitable nature of such beliefs or define certainty as a property of those beliefs with the greatest possible justification. Certainty is closely related to knowledge, although contemporary philosophers tend to treat knowledge as having lower requirements than certainty.Importantly, epistemic certainty is not the same thing as psychological certainty (also known as subjective certainty), which describes the highest degree to which a person could be convinced that something is true. While a person may be completely convinced that a particular belief is true, and might even be psychologically incapable of entertaining its falsity, this does not entail that the belief is itself beyond rational doubt or incapable of being false. While the word “certainty” is sometimes used to refer to a person’s subjective certainty about the truth of a belief, philosophers are primarily interested in the question of whether any beliefs ever attain objective certainty.
The philosophical question of whether one can ever be truly certain about anything has been widely debated for centuries. Many proponents of philosophical skepticism deny that certainty is possible, or claim that it is only possible in a priori domains such as logic or mathematics. Historically, many philosophers have held that knowledge requires epistemic certainty, and therefore that one must have infallible justification in order to count as knowing the truth of a proposition. However, many philosophers such as René Descartes were troubled by the resulting skeptical implications, since all of our experiences at least seem to be compatible with various skeptical scenarios. It is generally accepted today that most of our beliefs are compatible with their falsity and are therefore fallible, although the status of being certain is still often ascribed to a limited range of beliefs (such as “I exist”). The apparent fallibility of our beliefs has led many contemporary philosophers to deny that knowledge requires certainty.

Certain nasal sprays recalled due to risks including seizure and death

About sprays
Spray or spraying commonly refer to:

Spray (liquid drop)
Aerosol spray
Blood spray
Hair spray
Nasal spray
Pepper spray
PAVA spray
Road spray or tire spray, road debris kicked up from a vehicle tire
Sea spray, refers to aerosol particles that form in the ocean
Spraying, or the creation of a spray
Spraying (animal behavior), the action of an animal marking its territory with urine
The use of a spray bottle
The use of a sprayer
Aerial application of chemicals
Spray paintingSpray or spraying may also refer to:

Three forms of nasal spray are being recalled because they could contain too much of a man-made hormone used in treating conditions including a type of diabetes and frequent urination.

Ferring Pharmaceuticals is recalling the sprays “due to superpotency or amounts of desmopressin higher than specified,” according to a notice posted Wednesday by the U.S. Food and Drug Administration. 

Certain nasal sprays recalled due to risks including seizure and death

The risks associated with too much of the commercially-made hormone desmopressin involve abnormally low levels of sodium in blood, which could lead to seizure, coma and death, it stated.

Recalled product label

U.S. Food and Drug Administration

The trouble was detected during routine testing, with one non-fatal “adverse event” possibly associated with the issue reported in the U.S., the agency stated.

The recall involves DDAVP Nasal Spray 10 mcg/0.1mL, Desmopressin Acetate Nasal Spray 10 mcg/0.1mL and Stimate Nasal Spray 1.5 mg/mL.

Recalled product label

U.S. Food and Drug Administration

DDAVP and Desmopressin Acetate nasal sprays are used as antidiuretic replacement therapies in managing central cranial diabetes insipidus and temporary polyuria (excessive urination) and polydipsia (excessive drinking due to thirst) after head trauma or surgery in the pituitary region, the recall notice stated.

Stimate nasal spray is used in treating certain patients with hemophilia A or those with mild to moderate classic von Willebrand’s disease, a blood-clotting disorder.

Recalled product label

U.S. Food and Drug Administration

Batch numbers and expiration dates of the sprays being recalled can be found here.